Primary HIV Infection in Non-dimensional Form
by Mike Martin

On this page, you can vary the parameters in a system of three ordinary differential equations that model primary HIV infection.   Let s (t) measure the concentration of healthy T cells, i (t) measure the concentration of infected T cells, and v (t) measure the concentration of free virus particles.   The model equations are then:


Note that s (0) = s0,   i (0) = i0,   and   v (0) = v0.   The parameter b measures the relative strength of the infection process.   The parameters ε & θ are ratios of reference times, with ε the lifetime of an infected cell relative to a healthy cell and θ the lifetime of a virus particle relative to that of an infected cell.   Submit real values for all of the parameters to obtain graphical solutions of the system as functions of time.   A numeric solution on the interval [0, T] is produced using Mathematica's numerical ODE solver, NDSolve.   Initial values must be input.

Enter in the value of the parameters and select the plotting bounds, then press the "Plot" button.

b =  

ε =  

θ =  


s0 =  

i0 =  

v0 =  


T =  


References:

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